The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 30, 2024

Filed:

Mar. 20, 2018
Applicants:

Celldom, Inc., San Carlos, CA (US);

The Regents of the University of California, Oakland, CA (US);

Inventors:

Natalia Tkachenko, San Diego, CA (US);

Eugene Tkachenko, Del Mar, CA (US);

Alexander Groisman, San Diego, CA (US);

Edgar Gutierrez, Spring Valley, CA (US);

Assignees:

Celldom, Inc., San Carlos, CA (US);

The Regents of the University of California, Oakland, CA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
B01J 19/00 (2006.01); B01L 3/00 (2006.01); C12N 15/10 (2006.01); C12Q 1/02 (2006.01); C40B 40/06 (2006.01); G01N 33/50 (2006.01); G01N 33/543 (2006.01);
U.S. Cl.
CPC ...
B01J 19/0046 (2013.01); B01L 3/5085 (2013.01); C12N 15/1013 (2013.01); C12Q 1/02 (2013.01); C40B 40/06 (2013.01); G01N 33/5005 (2013.01); G01N 33/54366 (2013.01); B01J 2219/00317 (2013.01); B01J 2219/005 (2013.01); B01J 2219/00648 (2013.01); B01L 2300/0829 (2013.01); B01L 2300/0851 (2013.01); B01L 2300/0858 (2013.01);
Abstract

The present invention provides methods, systems and kits for performing microwell analysis in sealed small volumes. The microwells of the invention are sealed through the pairing of microwell and bead geometry wherein the diameter of the beads is greater than the diameter of the bottom of the microwells. Loading the beads into the microwells seals samples within an analytical space between the bottom of a nested bead and the bottom of the subject microwell.


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