The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 30, 2024
Filed:
Jul. 07, 2020
Applicants:
The Board of Regents of the University of Texas System, Austin, TX (US);
Edward Keefer, Dallas, TX (US);
Inventors:
Jonathan Cheng, Dallas, TX (US);
Edward Keefer, Dallas, TX (US);
Srikanth Vasudevan, Dallas, TX (US);
Assignees:
The Board of Regents of the University of Texas System, Austin, TX (US);
Other;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61L 27/18 (2006.01); A61K 38/18 (2006.01); A61K 45/06 (2006.01); A61K 31/395 (2006.01); A61K 31/5377 (2006.01); C07D 257/02 (2006.01);
U.S. Cl.
CPC ...
A61L 27/18 (2013.01); A61K 38/18 (2013.01); A61K 38/185 (2013.01); A61K 38/1866 (2013.01); A61K 45/06 (2013.01); A61K 31/395 (2013.01); A61K 31/5377 (2013.01); A61L 2430/32 (2013.01); C07D 257/02 (2013.01);
Abstract
The present disclosure describes the use of immune modulators to promote nerve growth and regeneration, particularly in the context of nerve deficit stemming from trauma and disease. In particular, the disclosure provides for the use of CXCR4 antagonsists, STAT3 activators, and an agent that increase nitric oxide, alone or in combination, to treat nerve deficit conditions.