The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 30, 2024
Filed:
Feb. 25, 2021
Applicant:
Translate Bio, Inc., Lexington, MA (US);
Inventors:
Shrirang Karve, Lexington, MA (US);
Ashish Sarode, Lexington, MA (US);
Frank DeRosa, Lexington, MA (US);
Assignee:
TRANSLATE BIO, INC., Lexington, MA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/02 (2006.01); A61K 9/51 (2006.01); A61K 47/60 (2017.01); A61K 47/69 (2017.01); A61K 48/00 (2006.01); B01F 23/451 (2022.01); B01F 33/301 (2022.01); B01J 13/20 (2006.01); B01F 101/22 (2022.01);
U.S. Cl.
CPC ...
A61K 48/0091 (2013.01); A61K 9/5123 (2013.01); A61K 47/60 (2017.08); A61K 47/6925 (2017.08); A61K 48/0033 (2013.01); B01F 23/451 (2022.01); B01F 33/3017 (2022.01); B01J 13/203 (2013.01); B01F 2101/22 (2022.01);
Abstract
The present invention provides an improved process for lipid nanoparticle formulation and mRNA encapsulation. In some embodiments, the present invention provides a process of encapsulating messenger RNA (mRNA) in lipid nanoparticles comprising a step of mixing a suspension of preformed lipid nanoparticles and mRNA.