The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 30, 2024

Filed:

Nov. 29, 2018
Applicant:

Kao Corporation, Tokyo, JP;

Inventors:

Rie Ninomiya, Fujisawa, JP;

Takafumi Nishijima, Tochigi, JP;

Noriko Sato, Tochigi, JP;

Assignee:

Kao Corporation, Tokyo, JP;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/7028 (2006.01); A61K 31/26 (2006.01); A61K 36/31 (2006.01); A61P 17/04 (2006.01); A61Q 19/00 (2006.01); C12Q 1/44 (2006.01); G01N 33/50 (2006.01);
U.S. Cl.
CPC ...
A61K 31/7028 (2013.01); A61K 31/26 (2013.01); A61K 36/31 (2013.01); A61P 17/04 (2018.01); C12Q 1/44 (2013.01); G01N 33/5023 (2013.01);
Abstract

To provide a method for evaluating or selecting an agent for reducing sensory irritation, which reduces sensory irritation caused by parabens, and an agent for reducing sensory irritation, which reduces sensory irritation caused by parabens. A method for evaluating or selecting an agent for reducing sensory irritation caused by parabens, comprising the following steps (1) to (3): (1) a step of contacting cells capable of expressing CES1 with a test substance; (2) a step of measuring expression of CES1 in the cells; (3) a step of evaluating a test substance which promotes expression of CES1 as an agent for reducing sensory irritation caused by parabens based on the results measured in (2).


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