The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 23, 2024
Filed:
Jul. 26, 2022
Applicant:
Renibus Therapeutics, Inc., Southlake, TX (US);
Inventors:
Richard A. Zager, Seattle, WA (US);
Donald Jeffrey Keyser, Southlake, TX (US);
Alvaro F. Guillem, Lantana, TX (US);
Assignee:
Renibus Therapeutics, Inc., Southlake, TX (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/68 (2006.01); A61K 31/277 (2006.01); A61K 31/409 (2006.01); A61K 33/26 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6893 (2013.01); A61K 31/277 (2013.01); A61K 31/409 (2013.01); A61K 33/26 (2013.01); G01N 2800/347 (2013.01);
Abstract
The p21 biomarker is utilized in the evaluation of whether a patient is suffering from kidney injury or failure, and can be used in methods of treating kidney injury or failure by determining the appropriateness of one or more of initiating renal replacement therapy, withdrawing delivery of compounds that are known to be damaging to the kidney, delaying or avoiding procedures that are known to be damaging to the kidney, and modifying diuretic administration.