The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 23, 2024

Filed:

Jul. 07, 2022
Applicant:

The Queen's University of Belfast, Belfast, GB;

Inventors:

Chris Watson, Belfast, GB;

Timothy Lyons, Belfast, GB;

Alice Cheung, Belfast, GB;

Clare Kelly, Belfast, GB;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/68 (2006.01); C07K 16/18 (2006.01);
U.S. Cl.
CPC ...
G01N 33/689 (2013.01); C07K 16/18 (2013.01); C07K 2317/34 (2013.01); G01N 2333/471 (2013.01); G01N 2800/368 (2013.01); G01N 2800/50 (2013.01);
Abstract

This invention relates to the use of biomarker LRG1 as a biomarker for preeclampsia for use from the first trimester. Elevated levels of leucine-rich alpha 2 glycoprotein 1 (LRG1) can predict risk for the future development of preeclampsia or other hypertensive disorders of pregnancy. The predictive test will comprise the measurement of LRG1 protein, peptide fragment, DNA or RNA, from either blood, plasma, serum, urine, saliva or amniotic fluid. The invention provides a method and a test kit to assess the risk of pre-eclampsia in pregnant woman. The method or test can utilise antibodies to measure levels of LGR1 in a sample.


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