The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 23, 2024
Filed:
Mar. 24, 2017
The Board of Regents of the University of Texas System, Austin, TX (US);
Kansas State University Research Foundation, Manhattan, KS (US);
Massoud Motamedi, Houston, TX (US);
Allan R. Brasier, Galveston, TX (US);
Stefan H. Bossmann, Manhattan, KS (US);
Christopher T. Culbertson, Manhattan, KS (US);
Deryl Troyer, Manhattan, KS (US);
Kansas State University Research Foundation, Manhattan, KS (US);
Board of Regents of The University of Texas System, Austin, TX (US);
Abstract
Methods and devices for microfluidic detection of a biological maker in a biospecimen collected from a subject are disclosed. The microfluidic devices include nanoparticle-based nanosensors comprising supramolecular recognition sequences, protease consensus sequences, post-translationally modifiable sequences, or sterically hindered benzylether bonds for specific interaction with a biological marker. Also disclosed are particular nanosensors for detecting cytokines, and other proteins based upon supramolecular recognition without chemical modification or enzymatic cleavage.