The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 23, 2024
Filed:
Sep. 26, 2019
University of Virginia Patent Foundation, Charlottesville, VA (US);
Nathan Swami, Charlottesville, VA (US);
John Mcgrath, Charlottesville, VA (US);
Walter Varhue, Glen Allen, VA (US);
Carlos Honrado, Charlottesville, VA (US);
Vahid Farmehini, Charlottesville, VA (US);
Yi Liu, Charlottesville, VA (US);
Nathan Swami, Charlottesville, VA (US);
John McGrath, Charlottesville, VA (US);
Walter Varhue, Glen Allen, VA (US);
Carlos Honrado, Charlottesville, VA (US);
Vahid Farmehini, Charlottesville, VA (US);
Yi Liu, Charlottesville, VA (US);
University of Virginia Patent Foundation, Charlottesville, VA (US);
Abstract
An exemplary method and system is disclosed that facilitate the integration of multiplexed single-cell impedance cytometry in a high throughput format, which can be deployed upstream from microfluidic sample preparation and/or downstream to microfluidic cell separation. In exemplary method and system may employ impedance-based quantification of cell electrophysiology on the same microfluidic chip (i.e., 'on-chip') to provide distinguishing phenotypic information on the sample, without the need for additional sample handling, preparation or dilution steps as would be needed for other flow cytometry techniques.