The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 23, 2024

Filed:

Feb. 06, 2020
Applicant:

Lonza Ltd., Visp, CH;

Inventors:

Thaddaeus Webster, Rollinsford, NH (US);

Carrie Mason, Brentwood, NH (US);

Tristan Wilkins, Newmarket, NH (US);

Assignee:

Lonza Ltd., Visp, CH;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12M 1/34 (2006.01); B01F 23/45 (2022.01); B01J 19/00 (2006.01); B01F 101/22 (2022.01);
U.S. Cl.
CPC ...
C12M 41/26 (2013.01); B01F 23/45 (2022.01); B01J 19/0086 (2013.01); C12M 1/3407 (2013.01); C12M 1/3453 (2013.01); C12M 41/12 (2013.01); B01F 2101/22 (2022.01); Y10T 436/108331 (2015.01);
Abstract

The monitoring and control of bioprocesses is provided. More particularly, the present disclosure is directed to formulating buffer products from multiple buffer solutions for feeding the different operations occurring within a bioprocess line. As the buffer product is being formulated, the buffer product is tested for conductivity, refractive index, and optionally pH. The conductivity measurements are used in conjunction with refractive index measurements to ensure that the buffer product not only has the correct concentration of ions but also has the correct concentration of components. A controller can be used to make automatic adjustments to the buffer product should any of the measured parameters fall outside a preset range.


Find Patent Forward Citations

Loading…