The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 23, 2024
Filed:
Sep. 17, 2018
Applicant:
Technische Universitaet Muenchen, Munich, DE;
Inventors:
Horst Otto Kessler, Schwalbach a. T., DE;
Chaim Gilon, Jerusalem, IL;
Amnon Hoffman, Jerusalem, IL;
Michael Weinmuller, Basel, CH;
Florian Rechenmacher, Munich, DE;
Joseph Fanous, Bat Yam, IL;
Adi Klinger, Rishon Lezion, IL;
Assignee:
TECHNISCHE UNIVERSITAET MUENCHEN, Munich, DE;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 7/64 (2006.01); A61K 9/00 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 7/64 (2013.01); A61K 9/0053 (2013.01); A61K 38/00 (2013.01);
Abstract
The present invention provides N-methylated cyclic hexapeptides comprising RGD and at least one alanine residue. The present invention further provides prodrugs comprising the cyclic hexapeptides. Pharmaceutical compositions comprising said cyclic hexapeptides are also disclosed as well as methods of their production and use in treating integrin related conditions and diseases.