The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 23, 2024

Filed:

Jun. 26, 2019
Applicants:

Kyowa Kirin Co., Ltd., Tokyo, JP;

Kagoshima University, Kagoshima, JP;

Inventors:

Nobuaki Takahashi, Tokyo, JP;

Ryosuke Nakano, Tokyo, JP;

Sayaka Maeda, Tokyo, JP;

Yuji Ito, Kagoshima, JP;

Assignees:

KYOWA KIRIN CO., LTD., Tokyo, JP;

KAGOSHIMA UNIVERSITY, Kagoshima, JP;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/30 (2006.01); C12N 5/16 (2006.01); G01N 33/50 (2006.01);
U.S. Cl.
CPC ...
C07K 16/3053 (2013.01); C12N 5/16 (2013.01); G01N 33/5058 (2013.01); C07K 2317/31 (2013.01); C07K 2317/565 (2013.01); C07K 2319/33 (2013.01);
Abstract

The invention relates to an antibody which binds to chondroitin sulfate proteoglycan 5 (CSPG5) or an antibody fragment thereof, a hybridoma which produces the antibody or the antibody fragment thereof, a nucleic acid comprising a nucleotide sequence encoding the antibody or the antibody fragment thereof, a transformant cell comprising a vector comprising the nucleic acid, a method for producing the antibody or the antibody fragment thereof, a composition comprising the antibody or the antibody fragment thereof, and a method for detecting or measuring an antigen present in the brain, a method for diagnosing or treating a brain disease, a method for enhancing the property of accumulating in a brain of an antibody, and a method for increasing the amount of an antibody in the brain, each of which using the antibody or the antibody fragment thereof, and the like.


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