The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 23, 2024
Filed:
Dec. 13, 2021
The Johns Hopkins University, Baltmore, MD (US);
Trustees of Boston University, Boston, MA (US);
William R. Bishai, Baltimore, MD (US);
John R. Murphy, Tilghman, MD (US);
Laurene Cheung, Baltimore, MD (US);
Shashank Gupta, Frederick, MD (US);
Cynthia K. Bullen, Baltimore, MD (US);
The Johns Hopkins University, Baltimore, MD (US);
Trustees of Boston University, Boston, MA (US);
Abstract
The present invention is a DNA expression vector comprising: a toxP: a mutant toxO that blocks Fe-mediated regulation of gene expression; and a DNA sequence encoding a protein, wherein the toxP and the mutant toxO regulate expression of the DNA segment encoding the protein. It is preferred that DNA expression vectors of the present invention include DNA sequences encoding a signal peptide so that a protein expressed is attached to the signal peptide prior to processing. Novel proteins are produced off of the DNA expression vector of the present invention.