The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 23, 2024

Filed:

Sep. 06, 2019
Applicant:

Array Biopharma Inc., Boulder, CO (US);

Inventors:

James F. Blake, Indianapolis, IN (US);

Donghua Dai, Indianapolis, IN (US);

Julia Haas, Indianapolis, IN (US);

Yutong Jiang, Indianapolis, IN (US);

Dean Kahn, Indianapolis, IN (US);

Gabrielle R. Kolakowski, Indianapolis, IN (US);

Elizabeth A. McFaddin, Indianapolis, IN (US);

Megan L McKenney, Indianapolis, IN (US);

Andrew T. Metcalf, Indianapolis, IN (US);

David A. Moreno, Indianapolis, IN (US);

Brett Prigaro, Indianapolis, IN (US);

Ginelle A. Ramann, Indianapolis, IN (US);

Li Ren, Indianapolis, IN (US);

Shane M. Walls, Indianapolis, IN (US);

Hailong Zhang, Indianapolis, IN (US);

Assignee:

ARRAY BIOPHARMA INC., Boulder, CO (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 498/22 (2006.01); A61K 31/519 (2006.01); A61K 31/55 (2006.01); A61K 31/554 (2006.01); A61K 45/06 (2006.01); A61P 35/00 (2006.01); C07D 487/14 (2006.01); C07D 498/14 (2006.01); C07D 513/22 (2006.01);
U.S. Cl.
CPC ...
C07D 498/22 (2013.01); A61K 31/519 (2013.01); A61K 31/55 (2013.01); A61K 31/554 (2013.01); A61K 45/06 (2013.01); A61P 35/00 (2018.01); C07D 487/14 (2013.01); C07D 498/14 (2013.01); C07D 513/22 (2013.01);
Abstract

Provided herein are compounds of the Formula (I): (I) and tautomers, stereoisomers and pharmaceutically acceptable salts and solvates thereof, wherein R, R, W, X, Y, Z, Ring A and (AA) have the meanings given in the specification, which are inhibitors of RET kinase and are useful in the treatment and prevention of diseases which can be treated with a RET kinase inhibitor, including RET-associated diseases and disorders.


Find Patent Forward Citations

Loading…