The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 23, 2024

Filed:

Feb. 05, 2018
Applicant:

Roche Molecular Systems, Inc., Pleasanton, CA (US);

Inventors:

Michael Glauser, Rotkreuz, CH;

Daniel Müller, Rotkreuz, CH;

Michael Zeder, Rotkreuz, CH;

Uta Schaffner, Rotkreuz, CH;

Assignee:

Roche Molecular Systems, Inc., Pleasanton, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2018.01); B01L 3/00 (2006.01); C12Q 1/6806 (2018.01); B01L 7/00 (2006.01);
U.S. Cl.
CPC ...
B01L 3/502715 (2013.01); C12Q 1/6806 (2013.01); B01L 3/50851 (2013.01); B01L 7/52 (2013.01); B01L 2200/027 (2013.01); B01L 2200/0605 (2013.01); B01L 2200/0642 (2013.01); B01L 2200/0673 (2013.01); B01L 2200/0684 (2013.01); B01L 2200/0689 (2013.01); B01L 2300/042 (2013.01); B01L 2300/048 (2013.01); B01L 2300/0816 (2013.01); B01L 2300/0864 (2013.01); B01L 2300/1805 (2013.01); B01L 2400/0406 (2013.01); B01L 2400/0487 (2013.01); B01L 2400/0677 (2013.01);
Abstract

The present disclosure relates to reversible sealing of a microfluidic chip used for thermal incubation of an aqueous sample suspected to contain a target nucleic acid. The microfluidic chip contains a flow channel and a plurality of reaction compartments, into which the sample and a displacement fluid are introduced through an inlet port sealable by means of a sealing agent having a melting point above room temperature.


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