The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 23, 2024
Filed:
Nov. 22, 2022
Applicant:
Fennec Pharmaceuticals Inc., Research Triangle Park, NC (US);
Inventor:
Alexander Smith, Apex, NC (US);
Assignee:
Fennec Pharmaceuticals Inc., Research Triangle Park, NC (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/20 (2006.01); A61K 9/00 (2006.01); A61K 9/08 (2006.01); A61K 33/04 (2006.01); A61K 33/243 (2019.01); A61K 47/02 (2006.01); A61K 47/18 (2017.01);
U.S. Cl.
CPC ...
A61K 47/20 (2013.01); A61K 9/0019 (2013.01); A61K 9/08 (2013.01); A61K 33/04 (2013.01); A61K 33/243 (2019.01); A61K 47/02 (2013.01); A61K 47/18 (2013.01); A61K 47/183 (2013.01);
Abstract
Described herein is anhydrous sodium thiosulfate, methods for synthesizing anhydrous sodium thiosulfate, pharmaceutical compositions thereof, and methods of treating ototoxicity. Anhydrous sodium thiosulfate is synthesized from sodium sulfite, sulfur, and cetylpyridinium chloride. The anhydrous sodium thiosulfate is formulated into a pharmaceutical composition comprising a buffer and solvent. These compositions are useful for eliminating or reducing ototoxicity in pediatric patients receiving platinum-based chemotherapeutics.