The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 23, 2024
Filed:
Apr. 25, 2017
Applicant:
Musc Foundation for Research Development, Charleston, SC (US);
Inventors:
Chrystal M. Paulos, Charleston, SC (US);
Michelle H. Nelson, Charleston, SC (US);
Stefanie R. Bailey, Charleston, SC (US);
Assignee:
MUSC Foundation for Research Development, Charleston, SC (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/17 (2015.01); A61K 38/19 (2006.01); A61K 39/00 (2006.01); A61P 35/00 (2006.01); C12N 5/0783 (2010.01); C12N 5/16 (2006.01);
U.S. Cl.
CPC ...
A61K 35/17 (2013.01); A61K 38/19 (2013.01); A61K 39/0011 (2013.01); A61K 39/001156 (2018.08); A61K 39/001168 (2018.08); A61P 35/00 (2018.01); C12N 5/0636 (2013.01); C12N 5/163 (2013.01); A61K 2039/5156 (2013.01); A61K 2039/5158 (2013.01); C12N 2510/00 (2013.01); G01N 2800/52 (2013.01);
Abstract
Provided herein are methods for the production of activated CD26high T cells by co-stimulation with inducible coactivator (ICOS). Further provided are methods for treatment of cancer by administration of the of activated CD26high T cells as an adoptive T cell therapy.