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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11963970 B1

PDFFull Text
Date of Patent:
Apr. 23, 2024

Filed:

Sep. 13, 2023

Preparation method of ginseng composition with high ginsenoside bioavailability

Applicants:

Jiangnan University, Wuxi, CN;

Standard Foods (China) Co., Ltd, Suzhou, CN;

Le Bonta Wellness Co., Ltd, Shanghai, CN;

Inventors:

Peng Zhou, Wuxi, CN;

Changshu Liu, Suzhou, CN;

Tao Yang, Wuxi, CN;

Chang Liu, Wuxi, CN;

Yaowei Liu, Wuxi, CN;

Zikuan Zhao, Wuxi, CN;

Jianguo Liu, Suzhou, CN;

Kexin Li, Shanghai, CN;

Assignees:

JIANGNAN UNIVERSITY, Wuxi, CN;

STANDARD FOODS (CHINA) CO., LTD, Suzhou, CN;

LE BONTA WELLNESS CO., LTD, Shanghai, CN;

Attorney:

IPRO, PLLC

Primary Examiner:

Qiuwen Mi

Int. Cl.
CPC ...
A61K 36/00 (2006.01); A61K 8/63 (2006.01); A61K 8/73 (2006.01); A61K 8/9789 (2017.01); A61K 31/704 (2006.01); A61K 36/258 (2006.01); A61K 47/40 (2006.01);
U.S. Cl.
CPC ...
A61K 31/704 (2013.01); A61K 8/63 (2013.01); A61K 8/738 (2013.01); A61K 8/9789 (2017.08); A61K 36/258 (2013.01); A61K 47/40 (2013.01); A61K 2236/15 (2013.01);
Abstract

The present disclosure discloses a preparation method of ginseng composition with high ginsenoside bioavailability. The composition is composed of ginseng powder of 250 meshes or more and β-cyclodextrin, and the mass ratio of the ginseng powder to the β-cyclodextrin is 1:0.05. Results show that when β-cyclodextrin is used as a solid dispersant and added to the 1000-mesh ginseng powder at a mass ratio of 5%, the total dissolution amount is maximum; and furthermore, animal experiments (SD rats) show that the area under the plasma drug concentration-time curve (AUC) after 48 h of ginseng powder ingestion is maximum, indicating that in-vivo bioavailability of the ginseng powder is the highest. The method of this application can effectively inhibit the aggregation of the ultra-finely pulverized 1000-mesh ginseng powder by adding the β-cyclodextrin, thus significantly improving the total dissolution amount of ginsenoside.

Find Patent Forward Citations

Zhou, Peng. (2024). Preparation method of ginseng composition with high ginsenoside bioavailability (U.S. Patent No. 11963970). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11963970

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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