The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 23, 2024

Filed:

Jan. 11, 2019
Applicant:

Centre for Eye Research Australia Limited, East Melbourne, AU;

Inventors:

Xavier Hadoux, East Melbourne, AU;

Flora Hui, East Melbourne, AU;

Peter Van Wijngaarden, East Melbourne, AU;

Jonathan Guy Crowston, East Melbourne, AU;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61B 3/10 (2006.01); A61B 3/12 (2006.01); A61B 3/14 (2006.01); A61B 5/00 (2006.01); A61B 5/145 (2006.01); A61B 5/1455 (2006.01); A61B 6/03 (2006.01); G01J 3/02 (2006.01); G06V 10/143 (2022.01); G06V 10/60 (2022.01); G06V 20/69 (2022.01); G06V 40/18 (2022.01); G16H 10/40 (2018.01); G16H 30/40 (2018.01); G16H 50/20 (2018.01); G16H 70/60 (2018.01); G06V 10/58 (2022.01);
U.S. Cl.
CPC ...
A61B 3/10 (2013.01); A61B 3/12 (2013.01); A61B 3/14 (2013.01); A61B 5/0075 (2013.01); A61B 5/14507 (2013.01); A61B 5/1455 (2013.01); A61B 5/4088 (2013.01); A61B 5/7264 (2013.01); A61B 6/037 (2013.01); G01J 3/0229 (2013.01); G06V 10/143 (2022.01); G06V 10/60 (2022.01); G06V 20/693 (2022.01); G06V 20/695 (2022.01); G06V 40/18 (2022.01); G16H 10/40 (2018.01); G16H 30/40 (2018.01); G16H 50/20 (2018.01); G16H 70/60 (2018.01); G06V 10/58 (2022.01);
Abstract

The present disclosure relates to a method and a system for quantifying a biomarker of a biological tissue. Two spectral sub-intervals are determined from a plurality of images of the tissue acquired at discrete wavelengths within a main wavelength interval using an imaging sensor in a manner such that the combination of the image data in the at least two spectral sub-intervals are correlated with a clinical variable of interest. The tissue is illuminated using one or more light sources with wavelengths within the at least two spectral sub-intervals. A measurement is of the light reflected by the tissue is acquired using an imaging sensor; and a measure of the biomarker of the tissue is calculated using the acquired measurement. The main wavelength interval is broader than each of the at least two spectral sub-intervals and at least one spectral confounder causing a spectral variability of the acquired image is present in the tissue.


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