The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 16, 2024
Filed:
Jan. 08, 2018
Applicant:
University of Rochester, Rochester, NY (US);
Inventors:
James Lionel McGrath, Rochester, NY (US);
Kilean Scott Lucas, Bozeman, MT (US);
Henry Hung Li Chung, Rochester, NY (US);
Assignee:
UNIVERSITY OF ROCHESTER, Rochester, NY (US);
Primary Examiner:
Int. Cl.
CPC ...
G01N 1/40 (2006.01); B01D 69/02 (2006.01); B01D 71/02 (2006.01); B01D 71/52 (2006.01); C12N 15/10 (2006.01);
U.S. Cl.
CPC ...
G01N 1/4005 (2013.01); B01D 69/02 (2013.01); B01D 71/02 (2013.01); B01D 71/52 (2013.01); C12N 15/1017 (2013.01); B01D 2325/027 (2013.01); B01D 2325/42 (2013.01); G01N 2001/4016 (2013.01);
Abstract
A device and method for isolating extracellular vesicles from biofluids is disclosed. A nanoporous silicon nitride membrane is provided with a tangential flow of biofluid. A pressure gradient through the nanoporous silicon nitride membrane facilitates capture of extracellular vesicles from the tangential flow vector of biofluid. Reversal of the pressure gradient results in the release of the extracellular vesicles for subsequent collection.