The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 16, 2024
Filed:
Aug. 27, 2021
Codexis, Inc., Redwood City, CA (US);
Societe Des Produits Nestle S.a., Vevey, CH;
Chinping Chng, Menlo Park, CA (US);
Nikki Dellas, San Carlos, CA (US);
Ravi David Garcia, Los Gatos, CA (US);
Moulay Hicham Alaoui Ismaili, San Mateo, CA (US);
Kristen Jean Vallieu, Union City, CA (US);
Kerryn McCluskie, Pacifica, CA (US);
Codexis, Inc., Redwood City, CA (US);
Societe des Produits Nestle S.A., Vevey, CH;
Abstract
The present invention provides engineered protease polypeptides and compositions thereof. The engineered protease polypeptides have been optimized to provide improved activity, improved thermostability, protease stability, autolytic stability, and stability under a range of pH conditions, including acidic (pH<7) and basic (pH>7) conditions. The invention also relates to the use of the compositions comprising the engineered protease polypeptides for therapeutic and/or nutritional purposes. The present invention also provides polynucleotides encoding the engineered protease polypeptides, as well as methods for making the engineered polynucleotides and protease polypeptides.