The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 16, 2024
Filed:
Dec. 17, 2018
Applicant:
Figene, Llc, Houston, TX (US);
Inventors:
Pete O'Heeron, Houston, TX (US);
Thomas Ichim, San Diego, CA (US);
Assignee:
Figene, LLC, Houston, TX (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/077 (2010.01); A61K 33/00 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0656 (2013.01); A61K 33/00 (2013.01); C12N 2500/02 (2013.01); C12N 2500/05 (2013.01);
Abstract
Embodiments of the disclosure include methods and compositions for use of prepared fibroblasts and/or conditioned media therefrom. In particular embodiments, the prepared fibroblasts have enhanced regenerative and may have an increase in secretion of one or more cytokines and/or growth factors; may have an increase in anti-apoptotic activity; and/or may have a modulated immunogenicity. In specific embodiments, the fibroblasts are prepared by exposure to hypoxia and/or carbon monoxide.