The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 16, 2024
Filed:
Jul. 27, 2023
Yeda Research and Development Co. Ltd., Rehovot, IL;
Yaqub Hanna, Tel Aviv-Jaffa, IL;
Sergey Viukov, Rehovot, IL;
Emilie Wildschutz, Rehovot, IL;
Noa Novershtern, Rehovot, IL;
Carine Joubran, Rehovot, IL;
Segev Naveh Tassa, Rehovot, IL;
Alejandro Castrejon Aguilera, Rehovot, IL;
Bernardo Oldak, Rehovot, IL;
Shadi Tarazi, Rehovot, IL;
Francesco Roncato, Rehovot, IL;
Yeda Research and Development Co. Ltd., Rehovot, IL;
Abstract
Methods of generating a synthetic embryo are provided. Accordingly, there is provided a method of generating a synthetic embryo comprising inducing expression of a factor that induces differentiation to trophectoderm cells in a subpopulation of naïve pluripotent stem cells (PSCs) to obtain a trophectoderm primed cells; inducing expression of a factor that induces differentiation to extra embryonic primitive endodermal cells in a second subpopulation of naïve PSCs to obtain extra embryonic primitive endodermal primed cells; and mixing said trophectoderm primed cells and said extra embryonic primitive endodermal primed cells with naïve PSCs under conditions that allow formation of aggregated cells. Also provided are articles of manufactures, mixtures and aggregates of cells and methods of using same.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile