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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11958976 B1

PDFFull Text
Date of Patent:
Apr. 16, 2024

Filed:

Oct. 27, 2022

Photoactive fluorophores and methods of in vivo labeling

Applicant:

Howard Hughes Medical Institute, Chevy Chase, MD (US);

Inventors:

Luke D. Lavis, Ashburn, VA (US);

Jonathan B. Grimm, Ashburn, VA (US);

Assignee:

HOWARD HUGHES MEDICAL INSTITUTE, Chevy Chase, MD (US);

Attorneys:

Stites & Harbison, PLLC

Mandy Wilson Decker

Primary Examiner:

Joseph R Kosack

Assistant Examiner:

Karen Cheng

Int. Cl.
CPC ...
C07D 405/12 (2006.01); C07D 311/80 (2006.01); C07D 313/14 (2006.01); C07D 473/32 (2006.01); C07D 493/10 (2006.01); C07F 7/08 (2006.01); C09B 11/24 (2006.01); C09B 11/28 (2006.01); G01N 21/64 (2006.01);
U.S. Cl.
CPC ...
C09B 11/24 (2013.01); C07D 311/80 (2013.01); C07D 313/14 (2013.01); C07D 405/12 (2013.01); C07D 473/32 (2013.01); C07D 493/10 (2013.01); C07F 7/0816 (2013.01); C09B 11/28 (2013.01); G01N 21/6458 (2013.01); G01N 2021/6439 (2013.01);
Abstract

Provided are a photoactive fluorophore, a photoactive ligand, and a photoactive complex. The photoactive fluorophore includes a photoactivatable derivative of an azetidine-containing Janelia-Fluor dye. The photoactive ligand includes a photoactive fluorophore and a protein tag. The photoactive complex includes a photoactive ligand conjugated to a protein. Also provided are methods of in vivo labeling with and photoactivation of the photoactive fluorophore, ligand, and complex.

Find Patent Forward Citations

Lavis, Luke. (2024). Photoactive fluorophores and methods of in vivo labeling (U.S. Patent No. 11958976). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11958976

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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