The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 16, 2024
Filed:
Feb. 17, 2020
Applicant:
The Trustees of the University of Pennsylvania, Philadelphia, PA (US);
Inventors:
Carl H. June, Merion Station, PA (US);
Sonia Guedan Carrio, Philadelphia, PA (US);
Yangbing Zhao, Cherry Hill, NJ (US);
John Scholler, Narberth, PA (US);
Assignee:
The Trustees of the University of Pennsylvania, Philadelphia, PA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A01N 63/00 (2020.01); A61K 35/12 (2015.01); A61K 48/00 (2006.01); C07K 14/705 (2006.01); C07K 14/725 (2006.01); C12N 5/10 (2006.01);
U.S. Cl.
CPC ...
C07K 14/705 (2013.01); A61K 35/12 (2013.01); C07K 14/70503 (2013.01); C07K 14/7051 (2013.01); C07K 14/70517 (2013.01); C07K 14/70521 (2013.01); C12N 5/10 (2013.01); C07K 2319/03 (2013.01);
Abstract
The present invention provides compositions and methods for treating cancer in a human. The invention includes administering a genetically modified Th17 cell to express a CAR having an antigen binding domain, a transmembrane domain, and an ICOS intracellular signaling domain.