The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 16, 2024

Filed:

Feb. 22, 2019
Applicant:

Fraunhofer-gesellschaft Zur Förderung Der Angewandten Forschung E.v., Munich, DE;

Inventors:

Christian Jäger, Halle, DE;

Linda Liebe, Halle, DE;

Daniel Ramsbeck, Halle, DE;

Miriam Linnert, Halle, DE;

Stefanie Geissler, Halle, DE;

Anke Piechotta, Halle, DE;

Diane Meitzner, Wolfen, DE;

Holger Cynis, Halle, DE;

Mirko Buchholz, Halle, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07F 15/02 (2006.01); A61P 31/04 (2006.01); C07D 471/04 (2006.01);
U.S. Cl.
CPC ...
C07F 15/025 (2013.01); A61P 31/04 (2018.01); C07D 471/04 (2013.01);
Abstract

The present invention relates to novel compounds which are particularly useful as inhibitors of bacterial glutaminyl cyclases (bacQC); pharmaceutical compositions comprising such compounds; compounds and/or pharmaceutical compositions for use in methods for treatment, in particular for use in the treatment of periodontitis and related conditions; as well as to crystals comprising bacterial glutaminyl cyclases, methods for identifying candidate compounds which may associate with the binding pocket of a bacQC and/or are bacQC inhibitors.


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