The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 16, 2024
Filed:
Feb. 24, 2022
Applicant:
Incyte Corporation, Wilmington, DE (US);
Inventors:
Stacey Shepard, Wilmington, DE (US);
Charles Cole, Wilmington, DE (US);
Nikoo Falahatpisheh, Wilmington, DE (US);
Kai Liu, Chadds Ford, PA (US);
Lixin Shao, Wilmington, DE (US);
Darius Vrubliauskas, Wilmington, DE (US);
Liangxing Wu, Wilmington, DE (US);
Wenqing Yao, Chadds Ford, PA (US);
Eddy W. Yue, Landenberg, PA (US);
Assignee:
Incyte Corporation, Wilmington, DE (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/22 (2006.01); A61P 35/00 (2006.01); C07D 471/18 (2006.01); C07D 471/20 (2006.01); C07D 491/22 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
C07D 491/22 (2013.01); A61P 35/00 (2018.01); C07D 471/18 (2013.01); C07D 471/20 (2013.01); C07D 471/22 (2013.01); C07D 519/00 (2013.01);
Abstract
The present application provides spirocyclic lactam compounds that modulate the activity of the V617F variant of JAK2, which are useful in the treatment of various diseases, including cancer.