The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 16, 2024
Filed:
Sep. 22, 2021
Board of Regents, the University of Texas System, Austin, TX (US);
Golgi Neurosciences S.r.l., Milan, IT;
Paolo Pevarello, Pavia, IT;
William J. Ray, Houston, TX (US);
Mary Hamby, Houston, TX (US);
Yaima Luzardo Lightfoot, Pearland, TX (US);
Philip Jones, Houston, TX (US);
Russell Thomas, Siena, IT;
Chiara Liberati, Milan, IT;
Domenica Torino, Praia a Mare, IT;
Valentina Cusano, Naples, IT;
Francesco Piscitelli, Marina di Strongoli, IT;
Ali Munaim Yousif, Aversa, IT;
Silvia Bovolenta, Milan, IT;
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM, Austin, TX (US);
GOLGI NEUROSCIENCES, S.R.L., Milan, IT;
Abstract
Disclosed herein are novel cycloalka[b]heteroaryl compounds having CX3CR1/fractalkine receptor (CX3CR1) agonistic properties, pharmaceutical compositions comprising these compounds, chemical processes for preparing these compounds and their use in the treatment or prophylaxis of diseases associated with CX3CR1 receptor activity in animals, in particular humans.