The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 16, 2024

Filed:

Aug. 23, 2019
Applicant:

Sintef Tto As, Trondheim, NO;

Inventors:

Ruth Schmid, Tiller, NO;

Peter Molesworth, Trondheim, NO;

Yrr Mørch, Trondheim, NO;

Einar Sulheim, Trondheim, NO;

Heidi Johnsen, Trondheim, NO;

Assignee:

SINTEF TTO AS, Trondheim, NO;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 9/51 (2006.01); A61K 45/06 (2006.01); B82Y 5/00 (2011.01);
U.S. Cl.
CPC ...
A61K 9/5138 (2013.01); A61K 9/5192 (2013.01); A61K 45/06 (2013.01); B82Y 5/00 (2013.01);
Abstract

The present invention provides a nanoparticle comprising a poly(alkyl cyanoacrylate) homopolymer, or copolymer, at least one active agent and an anionic and radical inhibitor, wherein the anionic and radical inhibitor is a compound having the following formula: wherein R1 is H; and R3, R4, R5, R6 and R7 are independently selected from the group consisting of —H, —OH, C1-C6 alkoxide, C1-C6 alkyl, halides, carboxylic acid, ketone or aldehyde; wherein the anionic and radical inhibitor is present in an amount of 0.001 to 15 wt %, as well as a process suitable for manufacture of the nanoparticle.


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