The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 16, 2024

Filed:

Mar. 25, 2019
Applicant:

Boehringer Ingelheim Animal Health Usa Inc., Duluth, GA (US);

Inventors:

Leigh Wilmes, Oregon, MO (US);

Matthew Coons, Dearborn, MO (US);

Amanda Brown, St. Joseph, MO (US);

Michael Johannes Gassel, Ingelheim am Rhein, DE;

Francois-Xavier Orveillon, Shanghai, CN;

Katharina Hedwig Toepfer, Hannover, DE;

Elida Bautista, St. Joseph, MO (US);

Kathy Schlesinger, St. Joseph, MO (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/12 (2006.01); A61P 31/20 (2006.01); C12N 15/86 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/12 (2013.01); A61P 31/20 (2018.01); C12N 15/86 (2013.01); A61K 2039/523 (2013.01); A61K 2039/5252 (2013.01); A61K 2039/5256 (2013.01); A61K 2039/5258 (2013.01); C12N 2710/14034 (2013.01); C12N 2710/14042 (2013.01); C12N 2710/14062 (2013.01);
Abstract

The present invention in particular relates to a method of producing an immunogenic composition exhibiting reduced virucidal activity, as well as to the immunogenic composition and uses thereof, wherein the method in particular comprises the steps of: (a) providing a mixture with a first liquid and a recombinant protein, (b) concentrating the recombinant protein in the mixture by removing a portion of the first liquid from the mixture, and (c) processing the solution resulting from step (b) by continuous diafiltration.


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