The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 16, 2024
Filed:
Mar. 25, 2021
Applicant:
Baylor Research Institute, Dallas, TX (US);
Inventors:
SangKon Oh, Baltimore, MD (US);
Sandra Zurawski, Midlothian, TX (US);
Hyemee Joo, Dallas, TX (US);
Gerard Zurawski, Midlothian, TX (US);
Assignee:
Baylor Research Institute, Dallas, TX (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/20 (2006.01); A61K 39/00 (2006.01); C07K 14/54 (2006.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
A61K 38/2066 (2013.01); A61K 39/0008 (2013.01); C07K 14/5428 (2013.01); C07K 16/2851 (2013.01); C07K 16/2878 (2013.01); A61K 2039/505 (2013.01); A61K 2039/54 (2013.01); A61K 2039/57 (2013.01); C07K 2317/24 (2013.01); C07K 2317/40 (2013.01); C07K 2317/52 (2013.01); C07K 2317/53 (2013.01); C07K 2317/56 (2013.01); C07K 2317/565 (2013.01); C07K 2317/73 (2013.01); C07K 2317/75 (2013.01); C07K 2319/00 (2013.01);
Abstract
Described herein are compositions and methods for inhibiting an inflammatory or autoimmune response and for inducing immune tolerance in a subject in need thereof comprising administering to the subject a therapeutically effective amount of an antigen presenting cell (APC)-targeted antibody operatively linked to IL-10 or a fragment thereof. The compositions and methods described herein are useful for treating inflammatory and autoimmune disorders.