The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 16, 2024

Filed:

Oct. 28, 2019
Applicant:

Biomet Manufacturing, Llc, Warsaw, IN (US);

Inventors:

Andrea Matuska, Gainesville, FL (US);

Krista Toler, Pierceton, IN (US);

Jennifer E. Woodell-May, Warsaw, IN (US);

Assignee:

Biomet Manufacturing, LLC, Warsaw, IN (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/20 (2006.01); A61K 35/14 (2015.01); A61K 35/19 (2015.01); A61K 35/28 (2015.01); A61K 38/17 (2006.01); A61K 38/18 (2006.01); A61K 38/19 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 38/1793 (2013.01); A61K 35/14 (2013.01); A61K 35/19 (2013.01); A61K 35/28 (2013.01); A61K 38/1808 (2013.01); A61K 38/1833 (2013.01); A61K 38/1858 (2013.01); A61K 38/19 (2013.01); A61K 38/20 (2013.01); A61K 38/2006 (2013.01); A61K 45/06 (2013.01);
Abstract

Methods of stimulating collagen production, including stimulation of chondrocyte production, at the site of a defect. Methods include administering to the site of a defect at least two proteins from the group IL-1ra, sTNF-RI, sTNF-RII, IGF-I, EGF, HGF, PDGF-AB, PDGF-BB, VEGF, TGF-β1, and sIL-1RII.


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