The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 16, 2024
Filed:
May. 05, 2022
President and Fellows of Harvard College, Cambridge, MA (US);
Metro International Biotech, Llc, Worcester, MA (US);
David A. Sinclair, Chestnut Hill, MA (US);
Jun Li, Brookline, MA (US);
Karl D. Normington, Prides Crossing, MA (US);
President and Fellows of Harvard College, Cambridge, MA (US);
Metro International Biotech, LLC, Worcester, MA (US);
Abstract
The invention provides methods of modulating and regulating NHD protein-protein interactions through nicotinamide mononucleotide, analogs and derivatives thereof, such as NAD. Such modulation may be useful in methods of treating and preventing cancer, aging, cell death, radiation damage, radiation exposure, among others, may improve DNA repair, cell proliferation, cell survival, among others, and may increase the life span of a cell or protect it against certain stresses, among others.