The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 16, 2024
Filed:
Jan. 12, 2023
Applicant:
The Trustees of Columbia University IN the City of New York, New York, NY (US);
Inventors:
Sinisa Vukelic, New York, NY (US);
Gerard A. Ateshian, New York, NY (US);
Assignee:
The Trustees of Columbia University in the City of New York, New York, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61F 9/008 (2006.01); A61B 18/00 (2006.01); A61B 18/04 (2006.01); A61B 18/20 (2006.01); A61B 18/26 (2006.01); A61B 90/00 (2016.01); A61N 1/44 (2006.01); A61N 5/06 (2006.01); A61N 5/067 (2006.01);
U.S. Cl.
CPC ...
A61F 9/008 (2013.01); A61B 18/042 (2013.01); A61B 18/203 (2013.01); A61B 18/26 (2013.01); A61B 90/361 (2016.02); A61N 1/44 (2013.01); A61N 5/062 (2013.01); A61B 2018/00702 (2013.01); A61B 2018/00785 (2013.01); A61B 2018/00791 (2013.01); A61B 2018/20359 (2017.05); A61B 2018/20553 (2017.05); A61B 2018/205545 (2017.05); A61B 2018/263 (2013.01); A61F 2009/00851 (2013.01); A61F 2009/00872 (2013.01); A61F 2009/00882 (2013.01); A61F 2009/00897 (2013.01); A61N 5/067 (2021.08);
Abstract
The presently disclosed subject matter provides techniques for inducing collagen cross-linking in human tissue, such as cartilage, by inducing ionization of the water contained in the tissue to produce free radicals that induce chemical cross-linking in the human tissue. In an embodiment, a femtosecond laser operates at sufficiently low laser pulse energy to avoid optical breakdown of the tissue being treated. In an embodiment, the femtosecond laser operates in the infrared frequency range.