The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 09, 2024
Filed:
Nov. 23, 2020
Exact Sciences Corporation, Madison, WI (US);
Mayo Foundation for Medical Education and Research, Rochester, MN (US);
David A. Ahlquist, Rochester, MN (US);
William R. Taylor, Lake City, MN (US);
Hongzhi Zou, Middleton, WI (US);
Graham P. Lidgard, Madison, WI (US);
Exact Sciences Corporation, Madison, WI (US);
Mayo Foundation for Medical Research and Education, Rochester, MN (US);
Abstract
The present invention relates to methods and compositions for determination of and uses of specific methylation patterns indicative of adenoma and carcinoma. In particular, the invention relates to analysis of defined CpG loci that are coordinately methylated in DNAs from cancer and adenoma samples, methods for identifying coordinately methylated loci, and methods of using analysis of coordinately methylated loci in one or more marker regions in the design of assays for adenoma and cancer.