The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 09, 2024
Filed:
Oct. 09, 2018
Medizinische Hochschule Hannover, Hannover, DE;
Twincore Zentrum Für Experimentelle Und Klinische Infektionsforschung Gmbh, Hannover, DE;
Technische Universität Dresden, Dresden, DE;
Daniel Todt, Hannover, DE;
Sibylle Haid, Hannover, DE;
Martin Wetzke, Hannover, DE;
Gesine Hansen, Hannover, DE;
Chris Lauber, Dresden, DE;
Lars Kaderali, Greifswald, DE;
Thomas Pietschmann, Hannover, DE;
MEDIZINISCHE HOCHSCHULE HANNOVER, Hannover, DE;
TWINCORE ZENTRUM FÜR EXPERIMENTELLE UND KLINISCHE INFEKTIONSFORSCHUNG GMBH, Hannover, DE;
TECHNISCHE UNIVERSITÄT DRESDEN, Dresden, DE;
Abstract
The present invention pertains to a method for the identification of genetic variants that are associated with the severity of an infectious disease. The invention further pertains to a set of genetic factors associated with the severity of Human respiratory syncytial virus (HRSV) infection, for example in human infants. The genetic polymorphisms identified according to the present invention are for use in the diagnostic of infectious diseases and patient stratification in order to avoid or reduce the occurrence of fatal events during infection or to elect the most appropriate therapeutic approach to treat the disease.