The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 09, 2024

Filed:

Jun. 09, 2021
Applicant:

Km Biologics Co., Ltd., Kumamoto, JP;

Inventors:

Kentaro Ebisu, Koshi, JP;

Takashi Kai, Koshi, JP;

Nozomi Matsuo, Kumamoto, JP;

Assignee:

KM Biologics Co., Ltd., Kumamoto, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 1/18 (2006.01); A61K 38/36 (2006.01); C07K 1/22 (2006.01);
U.S. Cl.
CPC ...
C07K 1/18 (2013.01); A61K 38/36 (2013.01);
Abstract

A chromatographic method for collecting blood coagulation factor VII (Factor VII) and/or activated blood coagulation factor VII (activated Factor VII) from plasma-derived fractions with high yield is provided. In accordance with the method of the present invention, Factor VII and/or activated Factor VII of interest can be collected with a recovery rate of as high as 90% or more by letting Factor VII and/or activated Factor VII which fails to be adsorbed to a first anion exchange resin and remains in a non-adsorption fraction be adsorbed in a second anion exchange resin.


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