The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 09, 2024
Filed:
Oct. 18, 2021
Pliant Therapeutics, Inc., South San Francisco, CA (US);
Jacob Cha, San Bruno, CA (US);
Manuel Muñoz, Vallejo, CA (US);
Maureen Reilly, Burlingame, CA (US);
Nicole Cooper, Oakland, CA (US);
Katerina Leftheris, San Mateo, CA (US);
David J. Morgans, Jr., South San Francisco, CA (US);
Timothy Hom, Sunnyvale, CA (US);
Yajun Zheng, Foster City, CA (US);
Christopher Bailey, Mountain View, CA (US);
Darren Finkelstein, Hillsborough, CA (US);
PLIANT THERAPEUTICS, INC., South San Francisco, CA (US);
Abstract
The invention relates to compounds of formula (I): or a salt thereof, wherein R, G, L, L, L, and Y are as described herein. Compounds of formula (I) and pharmaceutical compositions thereof are inhibitors of one, or both of, αvβintegrin and αvβintegrin that are useful for treating fibrosis such as in nonalcoholic steatohepatitis (NASH), idiopathic pulmonary fibrosis (IPF) and nonspecific interstitial pneumonia (NSIP).