The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 09, 2024
Filed:
Sep. 03, 2019
Applicant:
Tyligand Bioscience (Shanghai) Limited, Shanghai, CN;
Inventors:
Boyu Zhong, Irving, TX (US);
Tony Yantao Zhang, Fishers, IN (US);
Yiju Cao, Shanghai, CN;
Guangming Chen, Shanghai, CN;
Assignee:
TYLIGAND BIOSCIENCE (SHANGHAI) LIMITED, Shanghai, CN;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/14 (2006.01); A61K 31/4439 (2006.01); A61K 45/06 (2006.01); A61P 35/00 (2006.01); C07D 487/04 (2006.01);
U.S. Cl.
CPC ...
C07D 401/14 (2013.01); A61K 31/4439 (2013.01); A61K 45/06 (2013.01); A61P 35/00 (2018.01); C07D 487/04 (2013.01);
Abstract
A group of tropomyosin receptor kinase inhibitors including an amido-phenoxy-indazole structure fragment. These compounds show potent inhibitory effects on various oncogenic kinases, especially TRK, and thus can be used to treat tumors or cancers.