The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 09, 2024
Filed:
Nov. 29, 2022
Applicant:
Kabushiki Kaisha Toshiba, Tokyo, JP;
Inventors:
Mitsuko Ishihara, Setagaya, JP;
Eiichi Akahoshi, Shinagawa, JP;
Katsuyuki Naito, Bunkyo, JP;
Emi Nozaki, Shinagawa, JP;
Saeko Saruwatari, Kawasaki, JP;
Assignee:
KABUSHIKI KAISHA TOSHIBA, Tokyo, JP;
Primary Examiner:
Int. Cl.
CPC ...
C07D 243/08 (2006.01); A61K 9/127 (2006.01); C07C 229/30 (2006.01); C07D 211/14 (2006.01); C07D 233/02 (2006.01); C07D 241/04 (2006.01); A61K 31/7088 (2006.01);
U.S. Cl.
CPC ...
C07D 243/08 (2013.01); A61K 9/1271 (2013.01); C07C 229/30 (2013.01); C07D 211/14 (2013.01); C07D 233/02 (2013.01); C07D 241/04 (2013.01); A61K 31/7088 (2013.01);
Abstract
The present embodiment provides a compound represented by the formula (1):Q-CHR (1)(Q is a nitrogen-containing aliphatic group containing two or more tertiary nitrogens but no oxygen, and R is an aliphatic group containing a biodegradable group). From the compound in combination with other lipids such as a lipid capable of reducing aggregation, lipid particles can be formed. Further, the compound can be used for a pharmaceutical composition to deliver an activator into cells.