The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 09, 2024

Filed:

Jun. 21, 2021
Applicant:

Life Technologies Corporation, Carlsbad, CA (US);

Inventors:

Jonathan Schultz, Guilford, CT (US);

David Marran, Durham, CT (US);

Assignee:

Life Technologies Corporation, Carlsbad, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6869 (2018.01); B01L 3/00 (2006.01); G01N 27/447 (2006.01); G01N 35/10 (2006.01);
U.S. Cl.
CPC ...
B01L 3/502715 (2013.01); B01L 3/502 (2013.01); B01L 3/50273 (2013.01); B01L 3/502738 (2013.01); B01L 3/502746 (2013.01); B01L 3/502776 (2013.01); B01L 3/52 (2013.01); C12Q 1/6869 (2013.01); G01N 27/447 (2013.01); B01J 2219/00389 (2013.01); B01J 2219/00394 (2013.01); B01L 3/502769 (2013.01); B01L 2200/16 (2013.01); B01L 2300/0636 (2013.01); B01L 2300/0645 (2013.01); B01L 2300/0861 (2013.01); B01L 2300/0864 (2013.01); B01L 2300/0867 (2013.01); B01L 2300/0874 (2013.01); B01L 2300/0877 (2013.01); B01L 2400/0487 (2013.01); G01N 35/1002 (2013.01); G01N 35/1097 (2013.01); Y10T 137/0318 (2015.04); Y10T 137/0424 (2015.04); Y10T 137/85938 (2015.04);
Abstract

The invention provides a passive fluidics circuit for directing different fluids to a common volume, such as a reaction chamber or flow cell, without intermixing or cross contamination. The direction and rate of flow through junctions, nodes and passages of the fluidics circuit are controlled by the states of upstream valves (e.g. opened or closed), differential fluid pressures at circuit inlets or upstream reservoirs, flow path resistances, and the like. Free diffusion or leakage of fluids from unselected inlets into the common outlet or other inlets at junctions or nodes is prevented by the flow of the selected inlet fluid, a portion of which sweeps by the inlets of unselected fluids and exits the fluidics circuit by waste ports, thereby creating a barrier against undesired intermixing with the outlet flow through leakage or diffusion.


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