The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 09, 2024

Filed:

May. 03, 2021
Applicant:

Old Dominion University Research Foundation, Norfolk, VA (US);

Inventors:

Andrei G. Pakhomov, Norfolk, VA (US);

Olga N. Pakhomova, Norfolk, VA (US);

Shu Xiao, Norfolk, VA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61N 1/32 (2006.01); A61N 1/04 (2006.01); A61N 1/36 (2006.01); C12N 13/00 (2006.01);
U.S. Cl.
CPC ...
A61N 1/323 (2013.01); A61N 1/327 (2013.01); C12N 13/00 (2013.01); A61N 1/0412 (2013.01); A61N 1/0476 (2013.01); A61N 1/36 (2013.01);
Abstract

Provided herein are methods of generating a biologically effective unipolar nanosecond electric pulse by superposing two biologically ineffective bipolar nanosecond electric pulses and related aspects, such as electroporation and/or therapeutic applications of these methods to non-invasively target electrostimulation (ES) selectively to deep tissues and organs.


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