The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 09, 2024

Filed:

May. 20, 2022
Applicants:

The United States of America, As Represented BY the Secretary, Department of Health and Human Services, Bethesda, MD (US);

The University of Strathclyde, Scotland, GB;

Inventors:

Chintamani Atreya, Bethesda, MD (US);

Michelle Maclean, Scotland, GB;

John G. Anderson, Scotland, GB;

Scott J. MacGregor, Scotland, GB;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61L 2/00 (2006.01); A61L 2/08 (2006.01);
U.S. Cl.
CPC ...
A61L 2/0052 (2013.01); A61L 2/084 (2013.01); A61L 2202/122 (2013.01); A61L 2202/22 (2013.01);
Abstract

Disclosed herein are methods and devices for the inactivation of pathogens (e.g., bacteria, viruses, etc.) in ex vivo stored blood products, such as plasma and/or platelets, by means of directing visible light radiation from an illuminating device into blood product storage containers in order to achieve effective pathogen inactivation without the presence of an added photosensitising agent in the blood product. An exemplary apparatus includes a control unit that operates a light source that emits light in the wavelength region of about 380-500 nm which is directed onto blood product storage bags at sufficient intensity to penetrate the bag material and the opaque blood product therein in order to inactivate pathogens in the blood product but at dose levels that cause no significant detrimental effects on the blood product.


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