The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 09, 2024

Filed:

Jun. 28, 2017
Applicant:

Celltrion Inc., Incheon, KR;

Inventors:

Joon Won Lee, Incheon, KR;

Won Yong Han, Incheon, KR;

Su Jung Kim, Incheon, KR;

Jun Seok Oh, Incheon, KR;

So Young Kim, Incheon, KR;

Su Hyeon Hong, Incheon, KR;

Yeon Kyeong Shin, Incheon, KR;

Assignee:

Celltrion Inc., Incheon, KR;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 9/08 (2006.01); A61K 39/00 (2006.01); A61K 39/395 (2006.01); A61P 37/02 (2006.01); A61P 37/04 (2006.01); A61P 37/06 (2006.01); C07K 16/00 (2006.01); C07K 16/24 (2006.01); A61K 47/10 (2017.01); A61K 47/18 (2017.01); A61K 47/26 (2006.01);
U.S. Cl.
CPC ...
A61K 9/08 (2013.01); A61K 39/00 (2013.01); A61K 39/395 (2013.01); A61P 37/02 (2018.01); A61P 37/04 (2018.01); A61P 37/06 (2018.01); C07K 16/00 (2013.01); C07K 16/241 (2013.01); A61K 2039/505 (2013.01); A61K 47/10 (2013.01); A61K 47/183 (2013.01); A61K 47/26 (2013.01); C07K 2317/622 (2013.01);
Abstract

The present invention provides a stable liquid pharmaceutical formulation containing: an antibody or its antigen-binding fragment; a surfactant; a sugar or its derivative; and a buffer. The stable liquid pharmaceutical formulation according to the present invention has low viscosity while containing a high content of the antibody, has excellent long-term storage stability based on excellent stability under accelerated conditions and severe conditions, and may be administered subcutaneously.


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