The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 09, 2024

Filed:

Nov. 30, 2018
Applicant:

The Regents of the University of California, Oakland, CA (US);

Inventors:

Heather D. Maynard, Los Angeles, CA (US);

Natalie Boehnke, Los Angeles, CA (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 47/58 (2017.01); A61K 47/69 (2017.01); C07K 14/605 (2006.01); C08F 8/34 (2006.01); C08F 220/28 (2006.01); C08F 220/38 (2006.01); C08G 81/02 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
A61K 47/6903 (2017.08); A61K 47/58 (2017.08); C07K 14/605 (2013.01); C08F 8/34 (2013.01); C08F 220/282 (2020.02); C08F 220/385 (2020.02); C08G 81/025 (2013.01); A61K 38/00 (2013.01); C08F 2800/10 (2013.01); C08F 2810/20 (2013.01);
Abstract

Trehalose-based nanogels for stabilizing and controlled releasing biomolecules such as glucagons are disclosed. Specifically, trehalose-based nanogels comprise (a) a copolymer comprising first methacrylate units and second methacrylate units, wherein (i) the first methacrylate units comprise trehalose side chains; and (ii) the second methacrylate units comprise disulfide side chains; (b) dithiol cross-linkers; wherein the dithiol cross-linkers cross link the copolymer through the disulfide side chains of the second methacrylate units.


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