The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 09, 2024
Filed:
Feb. 18, 2019
Applicant:
Crescendo Biologics Limited, Cambridge, GB;
Inventors:
Carolyn Edwards, Cambridge, GB;
Angelica Sette, Cambridge, GB;
Isabelle Osuch, Cambridge, GB;
Yumin Teng, Cambridge, GB;
James Legg, Cambridge, GB;
David Escors Murugarren, Pamplona, ES;
Assignee:
CRESCENDO BIOLOGICS LIMITED, Cambridge, GB;
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); A61K 47/68 (2017.01); C07K 16/18 (2006.01); C07K 16/28 (2006.01); C12N 15/10 (2006.01); C07K 16/46 (2006.01);
U.S. Cl.
CPC ...
A61K 47/6801 (2017.08); A61K 39/3955 (2013.01); C07K 16/2818 (2013.01); C12N 15/10 (2013.01); C07K 16/28 (2013.01); C07K 16/2803 (2013.01); C07K 16/46 (2013.01); C07K 2317/31 (2013.01); C07K 2317/565 (2013.01); C07K 2317/569 (2013.01); C07K 2317/626 (2013.01); C07K 2317/94 (2013.01); C07K 2319/00 (2013.01);
Abstract
The invention relates to LAG-3 binding agents, in particular variable heavy chain (V) sdAbs and bispecific agents that target both LAG-3 and PD-1, and the use of such binding agents in the treatment, prevention and detection of disease.