The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 09, 2024
Filed:
Mar. 14, 2023
Skybio Llc, Miami, FL (US);
Consejo Nacional DE Investigaciones Científicas Y Técnicas (Conicet), Ciudad Autónoma de Buenos Aires, AR;
Universidad Nacional DE Tucumán, Tucumán, AR;
Universidad DE Buenos Aires, Buenos Aires, AR;
Sistema Provincial DE Salud DE Tucumán, Tucuman, AR;
Oscar José Varela, Ciudad Autonoma de Buenos Aires, AR;
Rosana Nieves Chehín, Tucumán, AR;
Cesar Luis Ávila, Tucumán, AR;
Sergio Benjamin Socías, Tucumán, AR;
Diego Ploper, Tucumán, AR;
Esteban Vera Pingitore, Tucumán, AR;
Analía Silvina Chaves, Tucumán, AR;
Martin Luong, Ciudad Autónoma de Buenos Aires, AR;
Verónica Elena Manzano, Ciudad Autónoma de Buenos Aires, AR;
Rodrigo Hernán Tomas Grau, Ciudad Autónoma de Buenos Aires, AR;
Maria Florencia González Lizárraga, Tucumán, AR;
Adriana Andrea Kolender, Ciudad Autónoma de Buenos Aires, AR;
Agustín Osvaldo Pernicone, Ciudad Autónoma de Buenos Aires, AR;
Skybio LLC, Miami, FL (US);
Consejo Nacional de Investigaciones Cientificas y Ténicas (Conicet), Ciudad Autónoma de Buenos Aires, AR;
Universidad Nacional de Tucumán, Tucumán, AR;
Universidad de Buenos Aires, Buenos Aires, AR;
Sistema Provincial De Salud De Tucumán, Tucuman, AR;
Abstract
The present disclosure provides a compound comprising a modified tetracycline derivative, covalently coupled through a linker to a low-hydrophobicity bioactive molecule useful for treating neurodegenerative diseases, wherein the modified tetracycline derivative is optionally defined by the following formula: