The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 02, 2024
Filed:
Mar. 09, 2021
New York University, New York, NY (US);
Spheryx, Inc., New York, NY (US);
David G. Grier, New York, NY (US);
Fook Chiong Cheong, Brooklyn, NY (US);
Kaitlynn Snyder, New York, NY (US);
Rushna Quddus, New York, NY (US);
Lauren E. Altman, New York, NY (US);
Kent Kirshenbaum, New York, NY (US);
New York University, New York, NY (US);
Spheryx, Inc, New York, NY (US);
Abstract
An in-line holographic microscope can be used to analyze a video stream to track individual colloidal particles' three-dimensional motions. The system and method can provide real time nanometer resolution, and simultaneously measure particle sizes and refractive indexes. An assay using the holographic microscope for holographic particle characterization directly detect viruses, antibodies and related targets binding to the surfaces of specifically functionalized micrometer-scale colloidal probe beads. The system detects binding of targets by directly measuring associated changes in the bead's diameter without the need for downstream labeling and analysis.