The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 02, 2024
Filed:
Jul. 30, 2019
Agency for Science, Technology and Research, Singapore, SG;
Agency for Science, Technology and Research, Singapore, SG;
Abstract
There is provided a method of assessing fibrosis in a tissue sample. The method includes: obtaining a stained image of a stained tissue sample, the stained tissue sample being stained in relation to collagen therein; producing a plurality of different types of collagen images based on the stained image, the plurality of different types of collagen images corresponding to a plurality of different types of collagen, respectively; determining a plurality of different types of collagen parameters based on the plurality of different types of collagen images using a deep neural network; and determining a degree of fibrosis in the stained tissue sample based on the plurality of different types of collagen parameters. The plurality of different types of collagen comprises portal collagen, fibrillary collagen and septal collagen. The different types of collagen images are produced by determining if the collagen satisfies a predetermined size condition or a predetermined distance condition with respect to a boundary of the portal tracts and central veins.