The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 02, 2024

Filed:

Feb. 21, 2019
Applicants:

Assistance Publique-hopitaux DE Paris, Paris, FR;

Centre National DE LA Recherche Scientifique (Cnrs), Paris, FR;

Institut National DE LA Sante ET DE LA Recherche Medicale (Inserm), Paris, FR;

Universite DE Paris, Paris, FR;

Ecole Nationale Superieure DE Chimie DE Paris, Paris, FR;

Inventors:

Hugo Salmon, Paris, FR;

Rabah Gahoual, Paris, FR;

Nathalie Mignet, Clamart, FR;

Pascal Houze, Beauchamp, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 30/00 (2006.01);
U.S. Cl.
CPC ...
G01N 30/0005 (2013.01); G01N 2030/003 (2013.01);
Abstract

The present invention relates to an asymmetric flow field-flow fractionation device () configured to separate a sample () of particles () dispersed in a liquid mobile phase (), the device including a fractionation microchannel () comprising a sample inlet, a sample outlet, an auxiliary microchannel () comprising an auxiliary outlet, a semipermeable membrane () separating the fractionation microchannel () and the auxiliary microchannel (), said membrane being permeable to liquid and being configured to maintain the particles () in said fractionation microchannel (), the fractionation microchannel () being superimposed on the auxiliary microchannel (), wherein the device () comprises two layers (), each layer being with a microfabricated recess () which thickness (t) is less than 100m, the membrane () being mechanically held in between the two layers (), the recesses () respectively defining the fractionation microchannel () and the auxiliary microchannel () on each side of the membrane ().


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