The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 02, 2024

Filed:

Mar. 06, 2023
Applicant:

The Regents of the University of California, Oakland, CA (US);

Inventors:

Bahram Jalali, Los Angeles, CA (US);

Eric D. Diebold, Los Angeles, CA (US);

Brandon Buckley, Los Angeles, CA (US);

Assignee:
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 15/14 (2006.01); G01N 15/10 (2006.01); G01N 15/1434 (2024.01); G01N 21/64 (2006.01); G01N 33/537 (2006.01);
U.S. Cl.
CPC ...
G01N 15/1434 (2013.01); G01N 15/1459 (2013.01); G01N 15/1484 (2013.01); G01N 21/64 (2013.01); G01N 33/537 (2013.01); G01N 2015/1006 (2013.01); G01N 2015/1477 (2013.01); G01N 2021/6421 (2013.01); G01N 21/6428 (2013.01); G01N 21/6458 (2013.01); G01N 21/6486 (2013.01); G01N 2201/067 (2013.01);
Abstract

An imaging flow cytometry apparatus and method which allows registering multiple locations across a cell, and/or across multiple flow channels, in parallel using radio-frequency-tagged emission (FIRE) coupled with a parallel optical detection scheme toward increasing analysis throughput. An optical source is modulated by multiple RF frequencies to produce an optical interrogation beam having a spatially distributed beat frequency. This beam is directed to one or more focused streams of cells whose responsive fluorescence, in different frequencies, is registered in parallel by an optical detector.


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